International Prostate Symptom Score Should Be Considered a Complement Rather Than a Substitute to Generic Preference-Based Measures for Measuring Lower Urinary Tract Symptoms Within Economic Evaluation

C Mpundu-Kaambwa; B Kaambwa; S Appleton; S Martin; G Wittert; R Adams

Journal article

International Prostate Symptom Score Should Be Considered a Complement Rather Than a Substitute to Generic Preference-Based Measures for Measuring Lower Urinary Tract Symptoms Within Economic Evaluation

C Mpundu-Kaambwa, B Kaambwa, S Appleton, S Martin, G Wittert, R Adams

Luts Lower Urinary Tract Symptoms | WILEY | Published : 2018

DOI: 10.1111/luts.12140

Abstract

Objective: To determine the suitability of using the International Prostate Symptom Score (IPSS), a condition-specific instrument, within economic evaluation of lower urinary tract symptom (LUTS) interventions. Methods: Data were obtained from a cohort of 2236 community-dwelling Australian men. Using correlations and a modified Bland–Altman plot, we investigated the convergent validity of the IPSS with two generic quality of life (GQol) instruments: the Assessment of Quality of Life 4 Dimensions (AQoL-4D) and the Short-Form 36 (SF-36). Discriminant validity was investigated using Wilcoxon–Mann–Whitney and Kruskal–Wallis tests, comparing instrument scores and utilities between subgroups varyi..

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University of Melbourne Researchers

Christine Mpundu-Kaambwa Author

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Grants

Awarded by ResMed Foundation

Funding Acknowledgements

This study was funded by a National Health and Medical Research Council of Australia Project Grant (627227). Financial support for the conduct of sleep studies was also obtained from the ResMed Foundation, California, USA. R. A. has received research funding from the National Health and Medical Research Council of Australia, and the ResMed Foundation, and non-financial support from Embla Systems, Colorado, USA. S. M. has received research funding from the National Heart Foundation of Australia.